head of cadd.

• Conceptualize, design and lead the company’s computational chemistry approach including drug design, cheminformatics, and in silico-based hit identification & optimization to accelerate the drug discovery process including both small molecule and biologics projects.
• Collaborate closely with medicinal chemists, biologists to support discovery research for preclinical development, and in vivo pharmacologists etc. to fulfill drug discovery goals.
• Provide expert opinion from computational point of view on target druggability, selectivity and discovery strategy.
• Provide leadership in solving specific project/technical issues to team members.
• Monitor the progress of discovery programs and impact the programs by contributing scientific ideas and solving critical issues.
• Be able to propose targets and initial new programs.

skills and experience required.

• PhD degree in computational chemistry, chemistry or closely related discipline
• 10+  years of industry experience in with a focus on CADD and strong understanding on both small molecule and biologics drug design.
• Expertise in molecular docking, homology modeling, molecular dynamics simulation and other technologies in CADD
• Expertise with state-of-art modeling and cheminformatics tools including Schrodinger, MOE, Convas, Vortex, Knime, etc. 
• A strong scientific track record of publications in peer-reviewed journals and/or patent literature is required.
• Proficiency with modern computational chemistry software and a strong technical understanding of the underlying principles for the techniques employed
• Proven ability to effectively collaborate with other functions to meet project goals.
• Excellent written and verbal communication skills are required, both in English and Chinese.